Table 5. Histologic and Neurologic Analyses of p35 Transgenic Rats in Comparison with Wild-type Animals

Values are expressed as mean ± SD.

Neuronal viability and TUNEL-positive neurons were not significantly different by intergroup comparison. Improved recovery in the NDS over time could be observed first in the p35 transgenic group of resuscitated animals (*P < 0.05 vs.  day 1). The long-term survival of p35 transgenic rats was substantially improved (†P < 0.05 vs.  wild-type).

NDS = neurologic deficit score; TUNEL = terminal deoxynucleotidyltransferase–mediated d-uracil triphosphate–biotin nick end-labeling.