Fig. 1. Time course of diastolic [Ca2+] and diastolic LVP before, during, and after 4-h ischemia at 17°C in CON, SPC, and SPC + 5-HD groups is shown. Diastolic [Ca2+] increased similarly in each group during cooling and hypothermic ischemia in each group, but was higher during reperfusion in the CON than other groups. Diastolic LVP increased similarly during cooling, but remained markedly elevated throughout reperfusion in the CON group compared with SPC groups.