Fig. 3. Dose-dependent effect of halothane on interleukin-6 (IL-6), macrophage inflammatory protein-2 (MIP-2), monocyte chemoattractant protein-1 (MCP-1), and total protein secretions by recombinant murine interleukin-1β (rmIL-1β)-stimulated alveolar type II cells. Recombinant mIL-1β-stimulated rat alveolar type II cells were exposed during 4 h to 0, 0.5, 1, and 1.5 minimum alveolar concentration of halothane. Cytokine concentrations were then measured in cell supernatants. Results are expressed as the percentage of values obtained for air-exposed cells, mean ± SD; †P < 0.05 and ‡P < 0.001 versus  air.