Fig. 1. The mean concentration of interleukin-6 (IL-6) in lung homogenates, measured using enzyme-linked immunosorbent assay, is shown (error bar is SD). Compared with phosphate-buffered saline (PBS)/control (n = 6), intratracheal endotoxin (lipopolysacharide [LPS]/control, n = 12) increased lung interleukin-6 concentration (*P < 0.05). Dobutamine infusion decreased this effect of endotoxin (LPS/Dobutamine, n = 13, †P < 0.05), whereas dopexamine had a lesser effect (LPS/Dopexamine, n = 13, P = nonsignificant).