Table 1. Effect of Isoflurane on the Hypoxic Pulmonary Vasoconstriction Response in the Absence and Presence of Potassium Channel Inhibitors

Values are mean ± SD (n = 6 per group).

*P < 0.01 versus  normoxia;

P < 0.01 versus  0 minimum alveolar concentration (MAC) in ΔPpawithin group.

Ppa= pulmonary arterial pressure (mmHg); Ppv= pulmonary venous pressure (mmHg); ΔPpa= the difference in Ppabefore and after hypoxic stimuli; flow = perfusion blood flow rate (ml/min); glib = glibenclamide, the adenosine triphosphate–sensitive potassium channel inhibitor; 4-AP = 4-aminopyridine, the voltage-sensitive potassium channel inhibitor; IbTX = iberiotoxin, the high-conductance calcium-activated potassium channel inhibitor.

Table 1. Effect of Isoflurane on the Hypoxic Pulmonary Vasoconstriction Response in the Absence and Presence of Potassium Channel Inhibitors
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