Fig. 3. Concentration-dependent effects of mexiletine on diazoxide (25 μm)-induced flavoprotein oxidation. The redox signal was normalized to the baseline flavoprotein fluorescence obtained during exposure to 5 μm 2,4-dinitrophenol at the end of the experiments. Each bar constitutes measurements from 10 single ventricular myocytes. *P < 0.05 versus  diazoxide alone.