Figure 2. Calculated dose-response curves (log dose scale) for loss of response to tetanic stimulus in patients with brain tumor and patients undergoing noncranial surgery. The 95% confidence intervals for the ED50s and ED95s are also displayed, slightly offset for clarity. Fraction of patients (of 10) who failed to respond to tetanic stimulus are shown as closed circles for patients with large brain tumor, as X for patients with small tumor, and as open circles for control patients.