Fig. 6. The effects of sevoflurane on spontaneous inhibitory postsynaptic currents (sIPSCs) in interneurons. Recording conditions were similar to those described in figure 3. (A ) Continuous recordings of sIPSCs (2 s/record) in control (top ) and in the presence of sevoflurane (2.7 vol%≈ 0.40 mm, bottom ). (B ) Sevoflurane-induced increase in sIPSC frequency plotted against experimental time. (C ) Sevoflurane effects on the amplitude distribution of sIPSCs and on the cumulative probability of sIPSCs.