Fig. 1. Experimental design: after a stabilization period of 30 min, a bolus dose of vecuronium bromide (950 μg) was given at t = 0, followed immediately by a continuous infusion (63 μg/min) throughout the liver perfusion. Between t = 30 and t = 60 min, the temperature in the gassing mixture was reduced to 28°C or not reduced (control). At t = 60, the temperature was normalized.