Figure 2. The interthreshold ranges (as defined by the difference between the sweating and vasoconstriction thresholds) were comparable on the control and the fever alone day: 0.5 +/- 0.5[degree sign]C versus 0.4 +/- 0.4[degree sign]C. In contrast, anesthesia (Anesth) significantly increased the interthreshold range to 1.9 +/- 0.6[degree sign]C. When desflurane and interleukin 2 were combined, the interthreshold range was 1.2 +/- 0.6[degree sign]C, which was significantly greater than during fever alone-but also significantly less than during anesthesia alone.