Fig. 3. The effect of strychnine on Aβ-, Aδ-, and C-fiber–evoked activity (16 stimuli of 3 × C-fiber threshold, 0.5 Hz, 2-ms-wide pulse) and postdischarge (PD) of a population of dorsal horn neurons in rats with spinal nerve ligation–induced neuropathy (circles) and nonoperated control animals (squares). Mean of the effect (± SEM) achieved 20 min after intrathecal administration of strychnine is plotted against the respective dose. In the spinal nerve ligation group, 7 cells were recorded after 1 μg strychnine, 6 after 10 μg strychnine, and 6 after 100 μg strychnine. In the nonoperated control group, n = 9, 9, and 8, respectively.