Fig. 1. (A ) The blood pressure effect of intravenous infusion of endotoxin at 1 (n = 6), 2 (n = 7), and 10 (n = 8) μg/kg on day 14 of pregnancy compared with sham control animals (n = 7). The mean arterial pressure (MAP) from days 1 to 14 of pregnancy (pretreatment, white bars) was compared with the mean value from days 14 to 21 of pregnancy (posttreatment, black bars). No significant change of MAP was observed after endotoxin infusion. (B ) The effect of intravenous infusion of endotoxin on urinary protein content. Endotoxin at 2 and 10 μg/kg significantly increased the urinary protein excretion. (C ) The effect of intravenous infusion of endotoxin on platelet count. Endotoxin at 2 and 10 μg/kg significantly decreased the platelet count. *P < 0.05.