Fig. 5. Effects of nitrous oxide and ketamine on NMDA and nACh receptors at different membrane potentials (n = 5). (A ) Inhibition of NR1a/NR2A NMDA receptors by nitrous oxide (0.58 atm) and ketamine (1 μm) was evaluated at membrane potentials of −100 and −30 mV. (B ) Inhibition of the α4β2 nACh receptors by nitrous oxide (0.58 atm) and ketamine (50 μm) at membrane potentials of −100 and −30 mV.