Fig. 3. Fifty percent response thresholds to von Frey filaments in (A ) untreated (open squares) or 1 mg/kg TX14(A)–treated (filled squares) control rats and (B ) untreated (open circles) or 1 mg/kg TX14(A)–treated (filled circles) diabetic rats. Data are median ± 95% confidence limits. n = 6 per group. Values at time points after TX14(A) injecton were compared with preinjection values by the Friedman test for nonparametric data and Dunn’s post hoc test. **P < 0.01 versus preinjection values.