Fig. 5. Time course of analgesia after injection of commercial 1% lidocaine solutions: plain lidocaine hydrochloride (▴ CL; pH = 6.6; n = 10); lidocaine hydrochloride alkalinized with NaOH (○ CLOH; pH = 7.8; n = 10); lidocaine hydrochloride alkalinized with 8.4% sodium bicarbonate (10:1; • CLBC; pH = 7.8; n = 10); control (⋄ n = 4).

Fig. 5. Time course of analgesia after injection of commercial 1% lidocaine solutions: plain lidocaine hydrochloride (▴ CL; pH = 6.6; n = 10); lidocaine hydrochloride alkalinized with NaOH (○ CLOH; pH = 7.8; n = 10); lidocaine hydrochloride alkalinized with 8.4% sodium bicarbonate (10:1; • CLBC; pH = 7.8; n = 10); control (⋄ n = 4).

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