Table 1. Predicted versus  Reported Changes in [HCO³⁻] after Saline Infusion in Dogs

* Weight range 14–25 kg; mean not provided; assumed extracellular volume (ECV) = 20% of mean body weight of 20 kg.

† Baseline not reported; only change reported; baseline assumed to be 24 mEq/l.

‡ Measured using chloride space.

§ 2,100 ml administered over 2 h; not adjusted for weight; mean weight assumed to be 20 kg.

[HCO³⁻]= serum bicarbonate concentration.