Fig. 3. Comparison of the relative (top ) and absolute (bottom ) approach to diagnose abnormalities in cold pain at the wrist. Open circles represent healthy individuals (threshold left side minus threshold right side), and filled circles represent CRPS I patients (threshold affected side minus threshold unaffected side). Lines refer to mean ± 2 SD. Note that normal values of the absolute approach are age-dependent and that two patients showed hypoalgesia with the relative approach.