Fig. 1. Relationship between local cerebral glucose utilization (LCGU) and local cerebral blood flow (LCBF) in normothermic, conscious (filled circles), normothermic, anesthetized (triangles), mildly hypothermic, anesthetized (35°C; squares), and moderately hypothermic, anesthetized (32°C, open circles) animals. For each of the examined 37 brain structures, the mean of the values of LCBF is plotted against the mean of the values of LCGU. The regression lines were calculated according to y = ax + b, with y being LCBF and x being LCGU. Normothermic conscious control group: y = 1.4x + 14, r = 0.94; normothermic anesthetized group: y = 2.4x + 40, r = 0.94; mildly hypothermic, anesthetized group: y = 3.6x + 16, r = 0.92; and moderately hypothermic, anesthetized group: y = 3.6x + 58, r = 0.95 (P < 0.05 between the slopes of all groups except for mild vs.  moderate hypothermia).