Fig. 1. Cortical infarct volumes produced by cortical AMPA. Isoflurane reduced infarct volume in a dose-dependent manner. The electroencephalogram burst-suppression dose (BS), but not the low dose (LD), of pentobarbital (Pent) reduced infarct volume. NBQX reduced infarct volume. The injury to the sham group was limited to a small infarction produced by the trauma of cannula insertion. *P < 0.05 versus  conscious group; #P < 0.05 versus  low-dose pentobarbital group; §P < 0.05 versus  1-MAC isoflurane group.