Fig. 5. Propofol infusion rates required to maintain a concentration of 1 μg/ml in a child (20 kg body weight, 5 yr of age), a lean adult (50 kg, 30 yr), an adult of average weight (70 kg, 70 yr), an obese adult (110 kg, 30 yr) and an elderly individual (65 kg, 80 yr). The infusion rates were calculated using the parameters of the final model (table 4).