Table 1. Steady-state Methylprednisolone Concentrations in Cerebrospinal Fluid and Spinal Cord Dialysates and Plasma

Steady state was determined by taking the mean dialysate or plasma concentration over the 100–240-min period for each animal.

IV = intravenous; IT = intrathecal; CSF = cerebrospinal fluid.

* Significant probability from the Mann–Whitney rank sum test.