Fig. 7. Comparative urinary excretion of mercapturic acids (detoxication) and β-lyase–derived fluoroacid metabolites (toxification) in humans and rats. Data for the alkane and alkene mercapturic acids and the β-lyase–derived 3,3,3-trifluoro-2-(fluoromethoxy)propanoic and trifluorolactic fluoroacid acid metabolites are summed. Human data are from this investigation (78 ± 58 ppm · h compound A). Rat data (n = 7) are from a previous investigation in which they received 46 ppm compound A by nose-only inhalation exposure for 3 h (138ppm · h). 7,26