Fig. 3. ( A ) The percentage of lung tumor retention (mean ± SEM). Animals were anesthetized and subjected to either normothermic or hypothermic conditions or served as controls. MADB106 cells were injected at T0or at 3 h. * A significant difference ( P < 0.02). ( B ) The number of lung tumor metastases (mean ± SEM) counted 4 weeks after MADB106 inoculation in normothermia, hypothermia, and in control animals. Tumor cells were injected at 2 h. * A significant difference ( P < 0.02).