Fig. 3. Systolic rate-pressure product (RPP, mean ± SD) values at various time points for each anesthetic group. Repeated-measures analysis of variance ( P = 0.02) indicated that the groups differed in RPP over time. Differences between groups were analyzed using the Bonferroni–Dunn post hoc test ( P < 0.017 is significant): group I versus II, P = 0.016; group I versus III, P < 0.0001; group II versus III, P = 0.10. Paired t tests with Bonferroni correction for multiple comparisons (with P < 0.01 significant) were used to compare RPP at each time point with the respective preoperative baseline value for each group. *Significantly increased compared with baseline values. **Significantly decreased compared with baseline values.