Figure 2. (A) The effect of hair deflection on catechol oxidation current (CA [middle dot] OC) peak height (% baseline) measured during a 60-min period from a microelectrode implanted in the locus coeruleus after intrathecal administration of 40 [micro sign]g strychnine ([black circle]) or saline ([white diamond]). Each hair deflection stimulus (5 min) is indicated by the horizontal bar (-) at the bottom of the figure. The effect of 30 [micro sign]g intrathecal ketorolac ([white circle]) on the CA [middle dot] OC peak height given 20 min before the 40 [micro sign]g strychnine injection is also illustrated. Each point represents the mean +/− SEM (n = 4). *P < 0.05 compared with prestrychnine levels. (B) The effect of hair deflection on peak mean arterial pressure after intrathecal administration of 40 [micro sign]g strychnine ([black circle]) or saline ([white diamond]). Each hair deflection stimulus (5 min) is indicated by the horizontal bar (-) at the bottom of the figure. The effect of 30 [micro sign]g intrathecally administered ketorolac ([white circle]) on the mean arterial pressure given 20 min before 40 [micro sign]g strychnine injection is also illustrated. The evoked increase in blood pressure is exposed as a percentage of baseline before hair deflection, and each point represents the mean +/− SEM (n = 4). *P 0.05 compared with prestrychnine levels.

Figure 2. (A) The effect of hair deflection on catechol oxidation current (CA [middle dot] OC) peak height (% baseline) measured during a 60-min period from a microelectrode implanted in the locus coeruleus after intrathecal administration of 40 [micro sign]g strychnine ([black circle]) or saline ([white diamond]). Each hair deflection stimulus (5 min) is indicated by the horizontal bar (-) at the bottom of the figure. The effect of 30 [micro sign]g intrathecal ketorolac ([white circle]) on the CA [middle dot] OC peak height given 20 min before the 40 [micro sign]g strychnine injection is also illustrated. Each point represents the mean +/− SEM (n = 4). *P < 0.05 compared with prestrychnine levels. (B) The effect of hair deflection on peak mean arterial pressure after intrathecal administration of 40 [micro sign]g strychnine ([black circle]) or saline ([white diamond]). Each hair deflection stimulus (5 min) is indicated by the horizontal bar (-) at the bottom of the figure. The effect of 30 [micro sign]g intrathecally administered ketorolac ([white circle]) on the mean arterial pressure given 20 min before 40 [micro sign]g strychnine injection is also illustrated. The evoked increase in blood pressure is exposed as a percentage of baseline before hair deflection, and each point represents the mean +/− SEM (n = 4). *P 0.05 compared with prestrychnine levels.

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