Figure 3. Displacement of [(3) H]diprenorphine binding to recombinant [micro sign](A), [small kappa, Greek](B), and [small delta, Greek](C) opioid receptors expressed in CHO cells by racemic (R(+/−)), S(+) and R(-) ketamine (K) and selective opioid receptor antagonists ([micro sign], cyprodime;[small kappa, Greek] norbinaltrophimine;[small delta, Greek] naltrindole). (D) The displacement curves for racemic ketamine alone. Full displacement curves are corrected for the competing mass of [(3) H]diprenorphine and are mean +/− SEM (n = 6).

Figure 3. Displacement of [(3) H]diprenorphine binding to recombinant [micro sign](A), [small kappa, Greek](B), and [small delta, Greek](C) opioid receptors expressed in CHO cells by racemic (R(+/−)), S(+) and R(-) ketamine (K) and selective opioid receptor antagonists ([micro sign], cyprodime;[small kappa, Greek] norbinaltrophimine;[small delta, Greek] naltrindole). (D) The displacement curves for racemic ketamine alone. Full displacement curves are corrected for the competing mass of [(3) H]diprenorphine and are mean +/− SEM (n = 6).

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