Figure 8. Tracings showing that 3% isoflurane-induced increases in submaximum Ca2+-activatedforce was enhanced by an inhibitor of calmodulin-dependent protein kinase II (KN-62). The tracings are representative of eight preparations. The strips were activated by 1 [micro sign]M Ca2+containing either 15% DMSO (A, control) or 0.1 mM KN-62 (B, KN-62) followed by solutions with the same compositions except saturated with 3% isoflurane.