Figure 7. The effect of inhibitors of protein kinase C on 3% isoflurane-induced increases in submaximum Ca^2+-activatedforce development. Means +/- SD (n = 7-10); force development activated by 1 [micro sign]M Ca²⁺at steady state after isoflurane administration expressed as a percentage of control force (before administration of isoflurane); TC = time control; Go = Go-6976 (10 [micro sign]M), and inhibitor of Ca^2+-dependentprotein kinase C; Bim = bisindolylmaleimide I-HCl (10 [micro sign]M), an inhibitor of Ca^2+-dependentand Ca^{2+-independent}protein kinase C. *P < 0.05 compared with that of time control. The isoflurane-induced increases (TC) in force were blocked by Bim but not by Go.