Figure 6. Hematoxylin and eosin stain of the microsphere injection site in sheep intercostal muscle. A-C show histology from intercostal injections with bupivacaine microspheres on day 0 (A) 100x, day 2 (B) 200x, and day 4 (C) 100x, respectively. D-F show intercostal muscle histology after injections with bupivacaine-dexamethasone microspheres on day 0 (D) 200x, day 2 (E) 200x, and day 4 (F) 200x. CT = connective tissue; E = edema; M = muscle; MS = microspheres;[arrow right]= polymorphonuclear leukocytes.

Figure 6. Hematoxylin and eosin stain of the microsphere injection site in sheep intercostal muscle. A-C show histology from intercostal injections with bupivacaine microspheres on day 0 (A) 100x, day 2 (B) 200x, and day 4 (C) 100x, respectively. D-F show intercostal muscle histology after injections with bupivacaine-dexamethasone microspheres on day 0 (D) 200x, day 2 (E) 200x, and day 4 (F) 200x. CT = connective tissue; E = edema; M = muscle; MS = microspheres;[arrow right]= polymorphonuclear leukocytes.

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