Figure 7. The effect of thiopental on myofilament Ca2+sensitivity was assessed by plotting twitch shortening (percent of resting cell length) as a function of peak [Ca2+]i(systolic fura-2 ratio) in the absence or presence of thiopental (100 [micro sign]M). [Ca2+]iwas varied by increasing [Ca2+]o. The shortening-[Ca2+]irelation obtained during control conditions (filled squares) was shifted to the left by thiopental (open circles).

Figure 7. The effect of thiopental on myofilament Ca2+sensitivity was assessed by plotting twitch shortening (percent of resting cell length) as a function of peak [Ca2+]i(systolic fura-2 ratio) in the absence or presence of thiopental (100 [micro sign]M). [Ca2+]iwas varied by increasing [Ca2+]o. The shortening-[Ca2+]irelation obtained during control conditions (filled squares) was shifted to the left by thiopental (open circles).

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