Figure 1. The time required for foot and core temperatures to equilibrate (within 0.3 [degree sign] Celsius) was reduced when the Ring and Messmer [15]anaphylaxis and anaphylactoid reaction severity scores were greater. Circles identify individual responses, with the adjacent squares showing the means and SDs. Asterisks (*) identify statistically significant differences from score 2. There was no significant difference between scores 3 and 4.