American Society of Anesthesiologists

Figure 1. Brain tissue PO2, PCO2, pH, and blood flow during etomidate and middle cerebral artery occlusion in patient 4. Each tracing is identified in the graph. Laser Doppler flow and pH are shown with bold lines. At the time of treatment with etomidate, PO(2) and blood flow decreased without a change in pH or PCO2. Middle cerebral artery occlusion produced a further decrease in PO(2) and blood flow and an increase in PCO2and acidosis. This patient showed a severe neurologic deficit postoperatively.

Figure 1. Brain tissue P^O², P^CO², pH, and blood flow during etomidate and middle cerebral artery occlusion in patient 4. Each tracing is identified in the graph. Laser Doppler flow and pH are shown with bold lines. At the time of treatment with etomidate, P^O(²) and blood flow decreased without a change in pH or P^CO². Middle cerebral artery occlusion produced a further decrease in P^O(²) and blood flow and an increase in P^CO²and acidosis. This patient showed a severe neurologic deficit postoperatively.

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