Figure 4. Lack of antagonism of the antinociceptive effect of intravenously administered morphine (2.5 mg/kg) by intrathecal injection of the NO synthase substrate, l-arginine (open circles) or the NO donor S-nitroso-N-acetylpenicillamine (SNAP; filled circles). Antinociception is expressed as percent maximum possible effect (%MPE). Data are presented as mean +/- SD.

Figure 4. Lack of antagonism of the antinociceptive effect of intravenously administered morphine (2.5 mg/kg) by intrathecal injection of the NO synthase substrate, l-arginine (open circles) or the NO donor S-nitroso-N-acetylpenicillamine (SNAP; filled circles). Antinociception is expressed as percent maximum possible effect (%MPE). Data are presented as mean +/- SD.

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