Figure 6. Effects of halothane on [sup 3 H]saxitoxin and [sup 3 H]brevetoxin-3 binding to synaptosomes. Synaptosomes were incubated with either 3 nM [sup 3 H]saxitoxin (open circles) or 25 nM [sup 3 H]brevetoxin-3 (filled circles) for 30 min at 37 [degree sign] Celsius (saxitoxin) or for 1 h at 4 [degree sign] Celsius (brevetoxin-3). Data represent mean +/- SD (n = 3) with duplicate determinations. *P < 0.05 versus control (no halothane) by analysis of variance with Fisher's post hoc test.