Figure 1. Systemic and microvascular hemodynamics during halothane or sevoflurane anesthesia. MAC = minimum alveolar concentration. The shaded area denotes the period when rats were treated with 2 MAC anesthesia. *P < 0.05 and **P < 0.01 for the 20-min study period (1 MAC). Arteriolar hemodynamics were well preserved in the sevoflurane group as compared with in the halothane group.