Figure 3. Anesthetic concentration-response data for halothane (filled squares), isoflurane (filled triangles), and desflurane (filled circles) in barium-containing Frog Ringer's solution. Data for the nonanesthetic agent 2N are shown with open circles. Measured concentrations are plotted in atmospheres (A) and micromoles per liter (B). Normalized response is the ratio of response of TOK1 cRNA-injected oocytes to voltage pulses (-80 to +40 mV) in the presence or absence of anesthetic agent. Mean values of normalized response are shown with standard errors of the means and best fit curves.