Figure 3. Relationship between observed plasma rocuronium concentration and that predicted by NONMEM's population analysis (A) and NONMEM's post hoc step (B) with the optimal three-compartment model. The x axis is time; the y axis is the ratio of observed to predicted concentrations of rocuronium. Each line is from a single individual. Dotted lines indicate the paleohepatic period; solid lines, the anhepatic period; and dashed lines, the neohepatic period. If the observed values were identical to the predicted values, each line would lie horizontally at 1.0.