Figure 6. Effects of halothane on intracellular inositol 1,4,5-triphosphate concentrations of thrombin-stimulated human platelets. The main figure shows the effect of 2 mM halothane on the time-dependent changes of the inositol 1,4,5-triphosphate induced by 0.02 units/ml thrombin. The inset shows the effects of halothane (0, 1, and 2 mM) on the peak inositol 1,4,5-triphosphate at 10 s after thrombin stimulation. Symbols represent means+/-SEM (n = 6 at each point). *P < 0.05, **P < 0.01 compared to the control values for the same time course.