Figure 1. A sample of electromyographic signals recorded after peripheral nerve stimulation. In this case, each waveform is the mean of 10 sweeps after stimulation at 1.55 mA of a rat equilibrated at the listed concentrations of sevoflurane. The leftmost deflection is an artifact that resulted from the stimulus pulse. Proceeding to the right in each wave is the M wave associated with orthodromic conduction from the site of stimulation. The M-wave amplitude is unaltered by sevoflurane in this dose range. The rightmost set of deflections represent the F-wave complex. Note the dose-related depression of F-wave amplitude, and in this rat, the apparent increase in latency between the M and F waves.