Figure 1. (A) Effects of 2% enflurane (ENF), 2% halothane (HAL), and 2% isoflurane (ISO) on the acetylcholine (ACh)-induced nitric oxide--mediated relaxation of the rabbit carotid artery (i.e., in the absence of NG-nitro-L-arginine). (B) Effects of 2% ENF, 2% HAL, 2% ISO, and (C) 8% desflurane (DES) and 2% sevoflurane (SEV) on the ACh-induced endothelium-derived hyperpolarizing factor-mediated relaxation of the rabbit carotid artery (i.e., in the presence of 100 micro Meter NG-nitro-L-arginine). *P < 0.05 versus control (CON); **P < 0.01 versus CON (n = 9-24). Where no error bar is shown, SEM falls within the dimensions of the symbol.