![Figure 1. Concentration-response relation for the negative chronotropic (atrial rate) (A) and negative dromotropic effects (atrioventricular nodal conduction time [AVNCT]) (B) of propofol in spontaneously beating guinea pig hearts. Each point is the mean plus/minus SEM of responses of five guinea pig hearts.](https://asa2.silverchair-cdn.com/asa2/content_public/journal/anesthesiology/83/2/10.1097_00000542-199508000-00019/2/19ff1.png?Expires=1716639879&Signature=rfSEvIi6CWLdq-Fvd9rks3PwIZyTaz-9UF3d3Hh5l1NRTbhUy0AbmDrkbvhB6ceTAoL0USkG3c2Lz4pO6hydgys9F0kQOpMqQplHBHuzFC-kJ3CS-fpYD~k0AHcHhkHsagLnBokWfsj1~f8t4PHWVk5Uega4c57TJA-OUftNQshUGFif~SABmHfyyCCSdBMqzBgJZdI3TuoOfNrdPQWUlOkUKHpPWMKP-qICkLRwwL54U70hPKYPNF6xfoZFOufVSvmvb9sJWcdD6D~a3JaIMJcK9BzSyAXS6Iu2qa0VxYVmkQn93Zkf0UY~PQQrkzAK-zyb7YGFU-c34fJJ9PuIQQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Figure 1. Concentration-response relation for the negative chronotropic (atrial rate) (A) and negative dromotropic effects (atrioventricular nodal conduction time [AVNCT]) (B) of propofol in spontaneously beating guinea pig hearts. Each point is the mean plus/minus SEM of responses of five guinea pig hearts.
