Figure 5. Comparison of different studies used to estimate the interaction of isoflurane and nitrous oxide. - - - ED50for suppression of learning, Dwyer et al. [22]-- - -- Minimum alveolar concentration-awake, Dwyer et al. [22]...- - Clinical signs, Eger et al. [21]--- Minimum alveolar concentration, Stevens et al., [4]Hornbein et al. [16].... Median electroencephalographic frequency 2-3 Hz (this study). Every point (*symbol*) represents the mean of a measurement.

Figure 5. Comparison of different studies used to estimate the interaction of isoflurane and nitrous oxide. - - - ED50for suppression of learning, Dwyer et al. [22]-- - -- Minimum alveolar concentration-awake, Dwyer et al. [22]...- - Clinical signs, Eger et al. [21]--- Minimum alveolar concentration, Stevens et al., [4]Hornbein et al. [16].... Median electroencephalographic frequency 2-3 Hz (this study). Every point (*symbol*) represents the mean of a measurement.

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