Figure 4. Effects of antibodies against CYP1A2, 2B1, 2C11, 2D1, and 3A2 on the catalytic activities of human hepatic microsomes. The ropivacaine concentration was 0.1 mM. The turnover rates of PPX, 4′-hydroxyropivacaine, and 3′-hydroxyropivacaine formation by human hepatic microsomes without antibodies were 0.560, 0.030, and 0.047 nanomoles per minute per milligram of microsomal protein, respectively.