Figure 2. Examples of developed pressure recordings from a control heart (A) or a heart to which HOE 642 and sevoflurane were added (B). Ischemia (I) and reperfusion (R) were each initiated for 60 min. The horizontal marker bar indicates 20 min, whereas the vertical bar indicates 20 mmHg developed pressure. Note the reduced increase in end-diastolic pressure with the drug combination and the more rapid and pronounced recovery of developed pressure, which reached a maximum value of 127% of preischemia values.