Figure 3. Arterial blood inulin concentration histories for the first 1.5 min (illustrating the first- and second-pass peaks) and for 360 min, or to the limit of detection (inset), after right atrial injection in one dog when it was awake (closed symbols) and when it was anesthetized with 2% halothane (open symbols). The symbols represent drug concentrations and the lines represent concentrations predicted by the models.