Fig. 3.
Ventilation, Axl inhibition and Axl shedding. (A) Ventilation with high tidal volume (20 ml/kg) in mice increases shedding of soluble Axl ectodomain (sAxl) compared to nonventilated (NV) animals (*P < 0.02, t test, n = 4). (B) R428 administration does not affect sAxl concentration in ventilated animals (Mann-Whitney, n = 4). BAL = bronchoalveolar lavage; ns = nonsignificant; Veh = vehicle.