Anesthesia effects on stationary intervoxel correlations within the macaque global neuronal workspace. Average correlation matrices for the awake state and anesthesia (ketamine anesthesia, moderate propofol sedation, deep propofol anesthesia, moderate sevoflurane sedation, and deep sevoflurane anesthesia; Student’s t tests, with the null hypothesis of zero correlation, P < 0.001, false discovery rate corrected). On the x-axis, arousal states. On the y-axis, regions from the macaque global neuronal workspace as defined in Uhrig et al.¹⁸  (ACC, PFCpol, FEF, PMCdl, S1, M1, Pcip, A1, TCi, V1, PCC of the left [L] and right [R] hemisphere). For each region (FEF [A], PFCdl [B]...), the matrix represents the functional correlation between the defined region (seed) and the remaining global neuronal workspace regions. Anesthesia decreases the functional correlation between the global neuronal workspace and its remaining areas such as FEF (A), PMCdl (C), ACC (D), Pcip (E), PCC (F), and A1 (G). However, anesthesia increases the functional correlation within prefrontal areas such as PFCdl (B). (I) Schematic representation of cerebral correlations of the macaque global neuronal workspace (ACC, PCC, PFCdl, FEF, PMCdl, Pcip, M1, S1, V1, A1; absolute correlation strength higher than 0.3) of the right hemisphere for the awake state and all anesthetic states. The results of the interregion ANOVA comparisons are displayed as P value matrices in Supplemental Digital Content, supplementary fig. 11, https://links.lww.com/ALN/B756. A1 = primary auditory cortex; ACC = anterior cingulate cortex; Amyg = amygdala; FEF = frontal eye fields; M1 = primary motor cortex; PCC = posterior cingulate cortex; PFCcl = centrolateral prefrontal cortex; PFCdl = dorsolateral prefrontal cortex; PFCdm = dorsomedial prefrontal cortex; PFCm = medial prefrontal cortex; PFCol = prefrontal polar cortex; PFCom = orbitomedial prefrontal cortex; PFCoi = orbitoinferior prefrontal cortex; PFCpol = prefrontal polar cortex; PFCvl = ventrolateral prefrontal cortex; PMCdl = dorsolateral premotor cortex; Pcip = intraparietal cortex; S1 = primary somatosensory cortex; TCi = inferior temporal; V1 = visual area 1; V2 = visual area 2.