Fig. 1.
Pathophysiology of capillary leak syndrome in critically ill burns. Fluid accumulation into the interstitium results from the combination of an imbalance between hydrostatic and oncotic forces favoring the fluid movement into the interstitium together with increase of vascular permeability and glycocalyx degradation. Red arrows indicate intravascular hydrostatic pressure, blue arrows indicate oncotic pressure, and green broken lines indicate glycocalyx. Π = Oncotic pressure.