Electrophysiologic properties of trigeminal ganglion neurons innervating the cancerous tongue. (A, B) Resting membrane potential (A) and rheobase (B) of trigeminal ganglion neurons innervating the tongue at the early and late stages after vehicle and squamous cell carcinoma (SCC) cell inoculation into the tongue. (C) The depolarization wave induced by the threshold current injection and current injection 50 pA smaller than the threshold. (D) The depolarization wave induced by the threshold current injection. (E) The depolarization wave induced by the 2× rheobase injection. (C–E) Passive and active properties (C, threshold; D, spike number at the rheobase; E, spike number of 2× rheobase) of trigeminal ganglion neurons innervating the tongue. The data represent means ± SD. Student’s t tests were used for statistical analysis.