The effect of sevoflurane before ⊖-burst stimulation on the induction of long-term potentiation (LTP). (A) Field excitatory postsynaptic potential (fEPSP) before (1) and after (2) the ⊖-burst stimulation (TBS) in slices not treated with sevoflurane (no sevoflurane); see (C) for the timing of these recordings. (B) fEPSP responses from slices treated with sevoflurane before TBS (sevoflurane before TBS): (1) before sevoflurane and TBS, and (2) after sevoflurane and TBS. (C) Sevoflurane reduces the fEPSP during its application. If sevoflurane application is discontinued before TBS, the initial slope of the fEPSP increases after TBS; LTP induction is not blocked by sevoflurane before TBS. All values are the mean ± SD; n = 7 for each group.